RNA Details
Disease Name
cardiomegaly
Tissue
heart
RNA Symbol
Agtrap
RNA ID
RNA Type
mRNA
Alteration Pattern
hyper methylation
Species
mus musculus
Detection Methods
PCR; Echocardiography
Target
NA
Pathway
NA
PubMed ID
Title
Hypomethylation of Agtrap is associated with long-term inhibition of left ventricular hypertrophy in prehypertensive losartan-treated spontaneously hypertensive rats.
Year
2017
Function
The hypomethylation of AGTARP accompanying upregulation of ATRP expression in the myocardium is associated with the long-term inhibition of left ventricular hypertrophy (LVH) in spontaneously hypertensive rats (SHRs) with prehypertensive losartan treatment.